Stopped: Study design flaws; research design needed to be reconfigured
Pediatric tonsillectomy is one of the most common surgical procedures annually in the United States; risks include postoperative hemorrhage and poor pain control. Controversy exists regarding optimal pharmacologic pain management following surgery, as each drug's efficacy is balanced by its specific side effects. Ibuprofen is effective in controlling postoperative pain following tonsillectomy, but its mechanism of action results in decreased platelet function, which may increase postoperative bleeding events. This is a multicenter, randomized control non-inferiority trial designed to assess the relationship between short-course ibuprofen use and post-tonsillectomy bleeding when compared to acetaminophen.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Post-tonsillectomy bleeding within 14 days of surgery.
Timeframe: Within 14 days of surgery