RecruitingEarly Phase 1

Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash

Egypt30 participantsStarted 2024-02-08

Plain-language summary

The objective of this study is to compare the effect of Tropolone containing mouthwash versus CHX 0.2% mouthwash in reducing intraoral microorganism. Randomized clinical trial study

Who can participate

Age range

18 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patients should be between 18- 45 years of age.
. All the volunteers participated in this study will be healthy looking with free medical history.
. The volunteers will be asked to suspend their usual oral hygiene practice from two to four days before experiment studying.

Exclusion criteria

. Patients with a compromised medical condition.
. Volunteers that receive any antimicrobial agent during at least two weeks prior to study.
. Volunteer with fixed, removable prosthesis or orthodontics appliance.
. Volunteers with DMF above six will be excluded.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Bacterial count.

Timeframe: Change from the baseline immediate after using mouthwash, at one week after mouthwash and at two weeks after regular use of mouthwash

Trial details

NCT IDNCT03384537

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-10

Contact for this trial

Mohamed Abdelkadir, master

+201117147699 mohamed.awad@dentistry.cu.edu.eg

View on ClinicalTrials.gov More Dental Diseases trials