CompletedNot Applicable

DSE vs. FFR in SCAD and BYSTANDER Lesions

200 participantsStarted 2014-12-01

Plain-language summary

Enrollment: * Patients with stable coronary artery disease (SCAD) and moderate coronary artery stenoses (30-70 %) * Patients with acute myocardial infarction and moderate stenosis of non-culprit arteries (NCL; BYSTANDER LESION) Aims: * To assess the diagnostic accuracy of dobutamine stress echocardiography (DSE) and invasive fractional flow reserve (FFR) measurement * To assess the prognostic impact of reclassification by a mismatching negative test Hypothesis: * DSE and FFR have similar prognostic value in both clinical settings (SCAD and NCL) * Considering the strong negative predictive value of both DSE and FFR, one negative test is sufficiently enough to defer revascularisation, even in the case of mismatch

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age\>18 years * Moderate Coronary Stenosis (30-70 %) * Stable coronary artery disease or patients with acute myocardial infarction and at least one moderate non-culprit vessel stenosis Exclusion Criteria: * Left Main Coronary artery stenosis * Age\>80 years * Known non-cardiovascular disease with poor prognosis * Patients for whom coronary angiography or stress echocardiography is contraindicated per institutional standard of care (e.g. History of severe and/or anaphylactic contrast reaction) * Inability to provide informed consent; * Inability to cooperate with the investigation * Pregnancy

What they're measuring

Acute Myocardial Infarction

Timeframe: From baseline to at least 2 years

Target Vessel Revascularisation

Timeframe: From baseline to at least 2 years

Cardiovascular Death

Timeframe: From baseline to at least 2 years

Trial details

NCT IDNCT03383718

SponsorBajcsy-Zsilinszky Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-12-01

View on ClinicalTrials.gov More Ischemic Heart Disease trials

Plain-language summary

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.