CompletedNot Applicable

The Effect of Per Oral Immunotherapy in Severe Milk, Peanut and Egg Allergy in Adults

Finland30 participantsStarted 2017-08-03

Plain-language summary

The aim is to analyse the results of per oral immunotherapy treatment in severe milk, peanut or egg allergy in adults. This is the second part of the oral immunotherapy study in adults at Skin and Allergy Hospital. The diagnosis of food allergy is verified with positive history, skin prick tests, egg and milk allergen specific IgE (immunoglobulin E) antibodies. In addition, food allergy is verified with an open label (milk allergy) or blind (peanut and egg allergy) allergen specific challenge test. OIT (oral immunotherapy) is performed according to a detailed plan. Lung function parameters are followed before OIT and and a year after OIT.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * severe milk, peanut or egg allergy verified with positive symptom history, skin prick tests and serum IgE tests and a challenge test Exclusion Criteria: * instable cerebrovascular or heart disease, active autoimmune disease or cancer, or current use of betablockers. * poorly controlled asthma or FEV1 \< 70% (FEV1\< -2SD)

What they're measuring

Desensitisation

Timeframe: 1 year, through study completion

Trial details

NCT IDNCT03361072

SponsorHelsinki University Central Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-03-11

Results submitted2023-10-13

View on ClinicalTrials.gov More Food Allergy trials