CompletedNot Applicable

Components of Social Functioning in Survivors of Pediatric Brain Tumors

United States80 participantsStarted 2018-01-30

Plain-language summary

Children with brain tumors are at risk for a number of psychological late effects, including neurocognitive and social deficits. This observational study focuses on assessment of social functioning, including social-cognitive and neurocognitive abilities, in survivors of pediatric brain tumors. This study will also assess the influence of medical factors, including diagnosis and age at diagnosis, on social functioning. PRIMARY OBJECTIVE: Examine the impact of social-cognitive and neurocognitive abilities on social functioning in survivors of pediatric brain tumors. SECONDARY OBJECTIVE: Assess the influence of medical factors such as diagnosis and age at diagnosis on the social functioning of survivors of pediatric brain tumors.

Who can participate

Age range8 Years – 12 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of medulloblastoma or other brain tumor * Current age between 8 and 12 years, inclusive * At least 2 years post-completion of therapy * Enrolled in school full-time * English speaking * Cognitive and language capacity to complete measures * Teacher inclusion: Consent received from survivor and parent to contact. * Best Friends inclusion: (1) Consent received from survivor and parent to contact, (2) English-speaking, (3) Cognitive capacity to complete questionnaires as judged by the parent during the consent process. Exclusion Criteria: * Diagnosis of a genetic disorder/pre-existing neurodevelopmental condition associated with neurocognitive or social impairment (e.g., autism, Neurofibromatosis Type 1 (NF1), Down syndrome * Homeschooled or full-time special education * IQ less than 70 as documented in the medical record * Inability or unwillingness of research participant or legal guardian/representative to give written informed consent. * Other tumor cohort exclusion: (1) diagnosis of craniopharyngioma, (2) treatment history includes craniospinal irradiation (CSI).

What they're measuring

Significant predictors of social-cognitive and neurocognitive abilities on social functioning

Timeframe: From enrollment through up to 7 days later

Trial details

NCT IDNCT03361033

SponsorSt. Jude Children's Research Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-10-17