CompletedNot Applicable

LOD Before IVF/ICSI in PCOS Patients With High AMH

Egypt120 participantsStarted 2013-03-22

Plain-language summary

To evaluate the effect of performing laparoscopic ovarian drilling (LOD) before proceeding to in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) on the cycle outcomes in polycystic ovarian syndrome (PCOS) patients with high antimullerian hormone (AMH) levels

Who can participate

Age range18 Years – 35 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * PCOS women subjected to COS through fixed gonadotropin releasing hormone (GnRH) antagonist protocol with final triggering of oocyte maturation by GnRH agonist (GnRHa) * Elevated serum AMH level (≥ 7 ng/ml) Exclusion Criteria: * Age \< 18 years or \> 35 years * Body mass index (BMI) \< 19 kg/m2 or \> 35 kg/m2 * Use of cabergoline therapy or coasting to minimize the risk of OHSS

What they're measuring

Number of oocytes retrieved

Timeframe: 36-38 hours after triggering of oocyte maturation

Oocyte maturity rate

Timeframe: Within one hour after oocyte retrieval

Fertilization rate

Timeframe: 20-24 hours after injection (or insemination)

Trial details

NCT IDNCT03358199

SponsorMansoura University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-05-31

View on ClinicalTrials.gov More Infertility trials