CompletedNot Applicable

The Role of Ischaemia-reperfusion Injury in the Pathogenesis of Muscle Wasting After Thoracic Aortic Surgery

40 participantsStarted 2013-11

Plain-language summary

Single-centre observational study over one year investigating the mechanisms of muscle homeostasis in patients with acute skeletal muscle atrophy following major aortic surgery

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All adult (\>18) patients undergoing major aortic or aortic valve surgery Exclusion Criteria: * Pre-existing cause for neuromuscular weakness or severe wasting (such as previous stroke, neuromuscular disease or malignancy)

What they're measuring

Change in Rectus Femoris muscle cross-sectional area (%)

Timeframe: 7 days

Trial details

NCT IDNCT03354767

SponsorImperial College London

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2014-10

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