CompletedNot Applicable

Agency in Dystonia

France76 participantsStarted 2017-10-23

Plain-language summary

In this study, using computerized cognitive assessments combined with multi-modal neuroimaging approach investigators aim to address three specific questions on patients with cervical and myoclonus dystonia: (i) investigate various aspects of the sense of agency and relationship to the severity of dystonia symptoms, (ii) characterize the possible link between abnormalities of movement perception and alteration of sense of agency in dystonia, (iii) (identify the neuronal underpinnings of the defective sense of agency in dystonia.

Who can participate

Age range15 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * diagnosis of isolated adult-onset cervical dystonia (CD) or myoclonus dystonia (MD); * duration of disease of more than one year * no botulinum toxin injection for at least three months before the study * normal or corrected-to-normal vision. Exclusion Criteria * any neurological history except for dystonia, * history of dopamine antagonist treatment, * secondary dystonia, * dystonia in the upper limbs, * inability to maintain gaze straight.

What they're measuring

agency tasks behavioral outcome measures

Timeframe: throughout study completion, an average 2 years

agency tasks behavioral outcome measures

Timeframe: throughout study completion, an average 2 years

Trial details

NCT IDNCT03351218

SponsorInstitut National de la Santé Et de la Recherche Médicale, France

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2020-10-15

View on ClinicalTrials.gov More Dystonia, Primary trials