Gastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination.

Inclusion Criteria: * Age ≥ 18 years * Biopsy proven primary adenocarcinoma (or undifferentiated carcinoma) of the stomach. Including tumours at the oesophagogastric junction provided that the bulk of the tumour is located in the stomach, and, the intended surgical treatment is a gastric resection and not an oesophagectomy. A high intra-thoracic anastomosis is allowed, but not if a thoracotomy is necessary. * cT3-cT4 tumour (TNM classification, 7th edition), considered to be resectable (including lymph nodes) * Limited peritoneal carcinomatosis (PCI \<7) and/ or tumour positive peritoneal cytology confirmed by laparoscopy or laparotomy and proven by pathological examination * Treatment with systemic chemotherapy, with the latest course ending within 8 weeks prior to inclusion. All currently standard chemotherapy regimens are acceptable * Absence of disease progression during systemic chemotherapy (prior to inclusion) * WHO performance status 0-2 * Adequate bone marrow, hepatic and renal function. Minimally acceptable laboratory values at start of the study inclusion: * ANC ≥ 1.5 x 109 /L * Platelet count ≥ 100 x 109 /L * Serum bilirubin ≤ 1.5 x ULN, and ALAT and ASAT ≤ 2.5 x ULN * Creatinine clearance ≥ 50 ml/min (measured or calculated by Cockcroft-Gault formula) * For female patients who are not sterilised or in menopause (i.e., amenorrhea ≥1 year if age ≥60 years, or ≥2 years if age \<60 years): * negative pregnancy test (urine/serum) * no breast feeding or …