Autologous Osteo-periosteal Cylinder Graft Transplantation for Hepple V Osteochondral Lesions of the Talus

Inclusion Criteria: * 18-50 years old, male or female * Chronic pain in the ankle, confirmed by ankle joint MRI as Hepple V osteo-chondral lesions of the talus * Using rest/external use/oral non-steroidal anti-inflammatory drugs and other conservative treatment for more than 3 months ineffective * Patients voluntarily participated in clinical trials, signed informed consent, with clinical follow-up Exclusion Criteria: * In the last 6 months patients participated in other drug or medical device clinical trials * Line of force in ankle is not correct (varus or valgus\> 5 degrees) * Grade III ankle collateral ligament injury * Chronic specific synovitis (rheumatoid, pigmented villonodular synovitis, etc.) * Joint fibrosis, ankylosis, activity was significantly limited * Moderate and severe osteoarthritis * There are MRI contraindications * Hemophilia patients * The general condition of patients can not tolerate surgery * Pregnant or planned pregnant women and lactating women * Abnormal mental capacity without autonomy * Other conditions in which the doctor can not decide to participate in the trial