A New Operation for the Treatment for Long-standing Atrial Fibrillation (NCT03347695) | Clinical Trial Compass
CompletedNot Applicable
A New Operation for the Treatment for Long-standing Atrial Fibrillation
China140 participantsStarted 2017-09-01
Plain-language summary
Atrial fibrillation(AF) often occurs in patients with mitral valve disease. Both mitral replacement and mitral valve plasty are the effective methods to the mitral valve disease. How to cure atrial fibrillation is the key to full recovery. Radiofrequency ablation (RFA) in surgery is an effective treatment for those patients. But there are some recurrence rate after RFA, particularly in patients with enlarged left atrium. So the investigators design a new procedure(Left Atrial Geometric Volume Reduction, Pulmonary Vein Island Isolation and Left Appendage Base Closure) during mitral surgery and study the outcomes to evaluate this new operation.
Who can participate
Age range18 Years – 75 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Able to sign Informed Consent and Release of Medical Information forms
✓. Age ≥ 18 years and ≤ 60 years old
✓. Clinical indications for only mitral valve surgery for the following:
✓. Longstanding persistent AF is defined as continuous AF of greater than one year duration.
✓. Able to use heart rhythm monitor
✓. Anteroposterior diameter of left atrial between 45mm and 60mm
Exclusion criteria
✕. Able to sign Informed Consent and Release of Medical Information forms
✕. Age ≥ 18 years
✕. Clinical indications for mitral valve surgery for the following:
✕. Longstanding persistent AF is defined as continuous AF of greater than one year duration.
What they're measuring
1
Numbers of Participants Free From AF
Timeframe: 3, 6, and 12 months after the operation