CompletedNot Applicable

Saliva Levels of S100A12, CRP, Fetuin-A in Periodontal Disease Patients

Turkey (Türkiye)54 participantsStarted 2017-02-01

Plain-language summary

Hs-CRP, Fetuin-A and S100A12 are acute phase proteins associated with many systemic diseases and conditions. The aim of this study was to determine the clinical parameters and salivary Hs-CRP, Fetuin-A and S100A12 levels before and after non-surgical periodontal treatments in the patients with periodontal diseases. A total of 54 subjects were divided in to three groups; periodontally healthy (n: 18), gingivitis (n: 18), chronic periodontitis (n: 18). Clinical periodontal parameters, salivary Hs-CRP, Fetuin-A and S100A12 levels and salivary flow rates were evaluated at baseline and a month after the treatments. Salivary Hs-CRP, Fetuin-A and S100A12 levels were assayed by ELISA.

Who can participate

SexALL

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Inclusion Criteria: never-smokers no history of systemic disease no patients had been under periodontal therapy and medicine for at least 6 months before the study no pregnancy or lactation no alcohol or antioxidant vitamin consumption. Exclusion Criteria: \-

What they're measuring

Salivary acute phase proteins

Timeframe: Baseline - a month after the periodontal treatments

Salivary acute phase proteins

Timeframe: Baseline - a month after the periodontal treatments

Salivary acute phase proteins

Timeframe: Baseline

Trial details

NCT IDNCT03345745

SponsorOrdu University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-06-01

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