CompletedNot Applicable

Effects of Inspiratory Muscle Training in Persons With Advanced Multiple Sclerosis

United States38 participantsStarted 2017-10-28

Plain-language summary

This study evaluates the effects of a 10-week inspiratory muscle training on the outcomes of respiratory muscle strength, fatigue, activity participation, and respiratory infection rates in persons with advanced Multiple Sclerosis (MS). Participants will perform daily exercise using the Threshold Inspiratory Muscle Trainer (IMT) device during the training period. The study will assess whether the participants improve after the training, and whether the effects can be maintained after the training ends.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Residents of The Boston Home * Diagnosis of multiple sclerosis by a physician * Expanded Disability Status Scale \>6.5 * Able to follow instructions in English Exclusion Criteria: * Hospitalization for exacerbation of MS within the previous 2 months * Unstable heart, lung, or other physical conditions * Current smoker * Oral temperature greater than 100 degrees Fahrenheit * Acute illness, such as infection, inflammation, ongoing chest pain, or short of breath with light activities * Current neurological diseases other than MS

What they're measuring

Change in Maximal inspiratory Pressure (MIP)

Timeframe: Baseline to 28 weeks

Change in Maximal Expiratory Pressure (MEP)

Timeframe: Baseline to 28 weeks

Trial details

NCT IDNCT03345199

SponsorUniversity of Michigan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-12-31

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