2 Arms (60 subjects - 30 each arm). Experimental group with two-pice zirconia dental implant and Control group with two-piece titanium dental implant Evaluate Changes in inflammatory and microbiology levels from T0 (baseline) T2 (8 weeks) and T3 (after crown placement) Also evaluate secondary outcomes: marginal bone loss (MBL), gingival height (GH) levels, osseointegration, gender, age, time of surgery, anatomical position and implant stability. p values\<0.05 were considered statistically significant
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Osseointegration
Timeframe: from T0 to T2 - 2 month
Marginal bone loss
Timeframe: 4 month after T0
IL1b concentration
Timeframe: 4 month
IL6 concentration
Timeframe: 4 month
Microbiologic samples
Timeframe: 4 month