CompletedNot Applicable

Prehospital High-Flow Nasal Oxygen Therapy

France58 participantsStarted 2017-12-21

Plain-language summary

The purpose of the present project is to compare High-Flow Nasal Oxygen therapy with Standard Oxygen therapy, initiated in the prehospital setting in patients with acute hypoxemia respiratory failure, in terms of oxygenation at arrival to the hospital and need of mechanical ventilation during the subsequent 28 days

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years * First SpO2 on scene \<90% * At least one other sign of respiratory distress defined by (a) respiratory distress with a respiratory rate ≥ 25/min; (b) laboured breathing * No advance directives or known decisions of Do Not intubate or Do Not Ventilate order. Exclusion Criteria: * Known COPD or other hypercapnic chronic respiratory failure * age \<18 years * Pregnancy or breastfeeding * Anatomical factors precluding the use of a nasal cannula * Emergency intubation required * Patients with tracheostomy * Patient transported to a hospital not involved in the study

What they're measuring

need of mechanical ventilation

Timeframe: 28 days

Trial details

NCT IDNCT03326830

SponsorCentre Hospitalier Régional d'Orléans

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-08-10

View on ClinicalTrials.gov More Acute Respiratory Failure With Hypoxia trials