UnknownNot Applicable

Influence of Different PEEP Levels and Tidal Volumes on Regional Lung Function

Germany40 participantsStarted 2018-01

Plain-language summary

Mechanical ventilation is indispensable for most of surgical interventions but can induce lung injury even in pulmonary healthy patients. This can lead to postoperative pulmonary complications. These adverse effects could be prevented by a better monitoring of intraoperative lung function. Electrical impedance tomography is able to visualize aeration within the lung in real time. The planned study investigates the influence of different levels of positive endexspiratory pressure and different tidal volumes on the aeration.

Who can participate

Age range18 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * over 18 years of age * scheduled for robot assisted prostate ectomy Exclusion Criteria: * body mass index \>35 kg/m² * chronic obstructive lung disease (GOLD III or IV) * obstructive sleep apnoe syndrome * planned or unplanned admission to intensive care unit for prolonged ventilation * mechanical ventialtion within the last 30 days * lung operation in the past * other lung disease that impairs activity

What they're measuring

Change of "dependent silent spaces" (DSS) and "non-dependent silent spaces" (NSS)

Timeframe: measurement of DSS and NSS are carried out prior to induction of anesthesia, 10 minutes after induction, 30 minutes after after installation of capnoperitoneum, 10 minutes after skin closure, 15 minutes after arrival at the PACU

Trial details

NCT IDNCT03326414

SponsorUniversitätsklinikum Hamburg-Eppendorf

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-04

Contact for this trial

Alexander März, MD

+40 40 7410 a.maerz@uke.de

View on ClinicalTrials.gov More Pulmonary Ventilation; Newborn, Abnormal trials