Efficacy of Lower Limb Exercises on Overactive Bladder Symptoms in Patients With Multiple Sclerosis

Inclusion Criteria: * Multiple Sclerosis Patients * Urge score \>=2 * urinary daytime frequency \>=8 * stable overactive bladder symptoms for 6 months * MRC ( Medical Research Council) scale of ankle plantarflexors and hamstrings \>=2 * signed informed consensus Exclusion Criteria: * FIM ( Functional Independence Measure) memory items \<=4 * impairment in registering bladder diary * inclusion in other experimental study * specific straightening during the suty period * PVR \>= 200 ml ina single evaluation or PVR (post void residual) \>=150 in 4 evaluation (twice a day for 2 consecutive days) * Urinary infections * concomitant urological disease * intrathecal baclofen pump * SANS (Stoller Afferent Nerve Stimulation) * modification of therapy for overactive bladder symptoms within three months before entering the study