Evaluation of the Expression and Functions of the KIR3DL2 Receptor and the Anti-inflammatory Activity of IPH4102 in Blood Samples

Inclusion Criteria: * Informed consent of the patient signed before any procedure planned to the protocol * SPA axial according to the criteria of the ASAS (international Assessment of SpondyloArthritis Society) * Known Status HLA B27 * Disease activates with a score of BASDAI = 4/10. The BASDAI (Bath Ankylosing Spondylitis Disease Activity Score) is a composite indication(index), validated, used in the therapeutic essays and in current practice for the evaluation of the activity of the SPA. * Naive Patients of thorough treatment * Patients of 18 and more years old Exclusion Criteria: * Minors * Pregnant or breast-feeding Women * Adults under guardianship * People staying in a sanitary or social establishment * People in emergency situation * Not profitable People of a national insurance scheme * Private persons of freedom * Treatment by corticoids during the last 30 days before the inclusion * Treatment by anti-TNF or quite different biomedicine * Treatment by sulfasalazine * Reached concomitant by another active chronic inflammatory disease * Infection chronicles by VHB, VHC or HIV * Patients included in another study of clinical trial