Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule… (NCT03321253) | Clinical Trial Compass
CompletedNot Applicable
Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule Opacification
38 participantsStarted 2015-10-23
Plain-language summary
It has been hypothesized that potential effects of laser Nd: YAG laser posterior capsulotomy may affect macular pigment as well as choroidal thickness, macular thickness and anterior chamber parameters, so it was aimed to investigate possible effects of Nd: YAG laser posterior capsulotomy on macular pigment optical density, choroidal thickness, macular thickness and anterior chamber parameters in cases with posterior capsule opacification in this study.
Who can participate
Age range
45 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Best-corrected visual acuity (BCVA) logMAR \<0.3
* Duration at least 2 years after cataract surgery
* Between the ages of 45 and 65 years (45≤age≤65)
Exclusion Criteria:
* Corneal scarring, diffuse posterior PCO or intravitreal hemorrhage that prevents appearance of the fundus
* Occluded angle by gonioscopy (grade 0, narrow angle, grade I, grade II)
* Presence of macular or peripheral retinal pathologies or choroidopathy
* High risk for RD
* Presence of macular edema in the macular area
* Detection of macular fluid or edema in OCT
* Active intraocular inflammation
* Previous laser PRP, Nd: YAG laser posterior capsulotomy, laser iridotomy or selective laser trabeculoplasty interventions
* Previous iridectomy, glaucoma or vitreoretinal surgery
* Glass intraocular lens
* Spherical refractive error ≥ ±6.00 D or cylinder refractive error ≥ ±3.00 D
* Inadequate stability of the eye
* Systemic diseases that may affect the choroidal blood flow such as cardiological diseases
* Current use of carotenoid supplementation
* Changing eating habits
* Gastrointestinal diseases that could cause disturbance of dietary absorption
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Changes of Foveal and Pericentral Pigment Optical Density (Log Unit) From Baseline at 2 Months
Timeframe: 2 months
2
Changes of Subfoveal, Temporal and Nasal Choroidal Thicknesses (Micrometer) From Baseline at 2 Months
Timeframe: 2 months
3
Changes of Anterior Chamber Depth (Millimeter) From Baseline at 2 Months
Timeframe: 2 months
4
Changes of Iridocorneal Angle From Baseline at 2 Months