Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia

Inclusion Criteria: * Adult or pediatric patient suffering from drug-resistant focal epilepsy; * Age more than 2 years old; * Brain MRI suggestive of FCD or normal; * Standardized presurgical evaluation available including medical history, scalp video-EEG, 3T MRI, FDG-PET, Neuropsychological tests; * Inpatient in one of the participating centers for recording seizure during long term scalp video-EEG and / or SEEG-monitoring; * Resective surgery with a minimal post-operative follow-up of 12 months; * Histopathologic evidence for FCD or non-pathologic findings (normal histology or mMCD type II). * Patient, parents or legally representative who have given written informed consent to allow the study data collection procedures. Exclusion Criteria: * Brain MRI suggestive of another type of lesion; * Difficulty to read or understand French, or inability to understand the information; * Pregnant or breastfeeding woman; * Subject under judicial protection. * Other lesion discovered on histological examination; * FCD type 3, dual pathology, ambiguous or unavailable neuropathological findings * Lack of longitudinal pre- and post-surgical follow-up.