UnknownNot Applicable

Impact of Nuclear Human Sperm Quality on Embryo Development

France200 participantsStarted 2017-01-02

Plain-language summary

To date, none study shows the impact of human spermatozoa nuclear alteration on embryonic development kinetic with morpho-kinetics tools. In this study, Investigator analyze the possible influence of sperm nuclear quality on embryonic development kinetics. Moreover, Investigator will evaluate possible new sperm biomarkers and try to better understand the pathophysiology of male infertility.

Who can participate

Age range18 Years – 37 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Couple whose wife is younger than 37 * First or second ICSI attempt at Clermont-Ferrand University hospital * Spermatozoa's concentration after Percoll gradients discontinuous technique is greater than or equal 0.5 million of spermatozoa * Number of oocytes injected in ICSI greater than or equal to 6 Exclusion Criteria: * If ICSI performed with testicular, epididymal or frozen spermatozoa * If one or both of the couple take antioxidant treatments

What they're measuring

embryonic development kinetics

Timeframe: 6 days after ICSI

Trial details

NCT IDNCT03320590

SponsorUniversity Hospital, Clermont-Ferrand

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-07-01

Contact for this trial

Patrick LACARIN

04 73 75 11 95 placarin@chu-clermontferrand.fr

View on ClinicalTrials.gov More Spermatic Parameters trials