P3 (Prepared, Protected, emPowered) is an interactive smartphone app for HIV-uninfected YMSM and YTW that utilizes social networking and game-based mechanics as well as a comprehensive understanding of what constitutes "best practices" in app development to improve PrEP adherence and persistence in PrEP care.
Who can participate
Age range16 Years ā 24 Years
SexMALE
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Are aged 16-24
* Were assigned male sex at birth
* Report sex with men or transgender women
* Are able to speak and read English
* Have reliable daily access to an Android or iOS smartphone with a data plan
* Are HIV-uninfected (self-report)
* Are not currently on PrEP but plan to initiate in the next 7 days and have an active PrEP prescription (prescription confirmed by study staff) OR on PrEP have an active PrEP prescription (prescription confirmed by study staff)
* Recruited from one of 9 subject recruitment venues (SRV) cities (Atlanta, Georgia; Boston, Massachusetts; Bronx, New York; Chicago, Illinois; Houston, Texas; Philadelphia, Pennsylvania; Tampa, Florida; Chapel Hill, NC; Charlotte, NC)
Exclusion Criteria:
* Aged younger than 15 years or older than 24 years
* Not available to meet with project staff for planned study visit(s)
* Non-English speaking
* Living with HIV
* Not currently prescribed PrEP (study staff unable to verify participant has an active PrEP prescription by a health provider)
* Anticipate not having reliable access to a smartphone with a data plan for 2 or more days during field testing or 1 or more weeks during the RCT intervention period
* Planning to move out of study area during the study period
* Unwilling or unable to comply with protocol requirements.
* Participated in field trial phase of P3 study
* Unable to be consented due to active substance use or psychological condition.
What they're measuring
1
PrEP Adherence Defined by Tenofovir Diphosphate (P3 and P3+ vs Control)
Timeframe: Month 3, Month 6
2
PrEP Adherence Defined by Emtricitabine Triphosphate (P3 and P3+ vs Control)