CompletedNot Applicable

Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute Disease

Denmark10 participantsStarted 2017-12-07

Plain-language summary

This study compares three different protein supplements (casein, whey and leucine-enriched whey) and their effect on post-inflammatory muscle waste in a model of acute disease. Each test person will undergo all three interventions. It is believed that leucine is the primary driver of muscle protein synthesis and therefore we hypothesize that leucine-enriched whey and whey are superior to casein in combating post-inflammatory muscle waste, because of its higher leucine content (16%, 11% and 9% leucine, respectively).

Who can participate

Age range20 Years – 40 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy Male * Age between 20-40 * BMI between 20-30 * Normal health examination and blood samples * Written informed consent Exclusion Criteria: * Immobilisation of an extremity, unless a doctor has declared it fully rehabilitated. * Allergy against lidocain or latex. * The use of anabolic steroids * Disease like: Diabetes, epilepsia, infection, cardiovascular disease.

What they're measuring

Change in muscle phenylalanine netbalance over the forearm muscle

Timeframe: Change from baseline to 3.5 hours after intervention

Trial details

NCT IDNCT03319550

SponsorUniversity of Aarhus

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-09-19

View on ClinicalTrials.gov More Muscle Protein Synthesis trials