CompletedNot Applicable

Pregnancy, Nitrate, Endothelial Function and Tissue Oxygen Saturation

12 participantsStarted 2016-10-06

Plain-language summary

Adequate macro and microvascular endothelial function during pregnancy is essential for the normal placental development and growing fetus. Beetroot juice (BJ) promotes improvement ins this parameters in no-pregnant individuals, however the beneficial effect did not avaliated in pregnant. The present study evaluated effects of BJ on macro and microvascular endothelial function in pregnant. Twelve pregnant were submitted to BJ and nitrate-depleted juice (PLA) interventions. Brachial flow-mediated dilation (FMD) and muscle oxygenation were measured 120 min after interventions. Urinary nitrate, nitrite were measured at baseline and 120 min after interventions.

Who can participate

Age range18 Years – 35 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * gestation between 20 and 35 weeks; * over 18 years Exclusion Criteria: * diabetes mellitus and gestational diabetes; * hypertensive syndromes; * HIV positive; * liver or kidney disease; * beetroot allergy; * use of antioxidants and medicament that alter endothelial function; * use of antibiotics up to 2 weeks before the visits and using.

What they're measuring

Macro endothelial function

Timeframe: Evaluated 120 minutes after the nutritional intervention

Micro endothelial function

Timeframe: Evaluated 140 minutes after the nutritional intervention

Nitrate urinary

Timeframe: Evaluated 150 minutes after the nutritional intervention

Trial details

NCT IDNCT03315806

SponsorUniversidade Federal do Rio de Janeiro

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-02-14

View on ClinicalTrials.gov More Pregnancy trials