UnknownNot Applicable

Mechanical Ventilation in Multiple Fracture Ribs

Egypt60 participantsStarted 2017-10-25

Plain-language summary

Chest trauma is the most common injury in the emergency trauma and rib fractures is the most common trauma in chest trauma. Severe rib fractures can cause paradoxical respiration and mediastinal swing, which has large effects on respiratory and circulatory system, result in acute respiratory distress syndrome. Mechanical ventilation can significantly improve the hypoxemia of the patients, correct paradoxical respiration, and treat the pulmonary atelectasis

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: • Isolated chest trauma patient with Multiple fracture ribs patients \[ \>3 ribs\] who will be admitted to the surgical ICU for ventilatory support and will be expected to continue for 2 days or longer Exclusion Criteria: * Age \< 18 years old. * Pregnant patient. * Patient who will require fraction of inspired oxygen more than 0.6. * Air leak from the chest tube. * Patient with body temperature \> 39 Celsius. * Acute hepatitis or severe liver disease (Child-Pugh class C). * Left ventricular ejection fraction less than 30%. * Heart rate less than 50 beats/min. * Second or third-degree heart block. * Systolic pressure \< 90 mmHg despite of infusion of 2 vasopressors. * Patients with known endocrine dysfunction. * Patient with hypothermia * Patient on Positive end expiratory pressure more than 14 cmH2o

What they're measuring

Duration of mechanical ventilation

Timeframe: within one month

Trial details

NCT IDNCT03314701

SponsorAssiut University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-10

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