Continuous vs Aerobic Postexercise Hypotension (NCT03313375) | Clinical Trial Compass
TerminatedNot Applicable
Continuous vs Aerobic Postexercise Hypotension
Stopped: Loss of funding and personnel
United States6 participantsStarted 2017-10-05
Plain-language summary
This study examines the effect of obesity and gender on postexercise hypotension with three different randomized exercise protocols or varying intensity. Subjects will be separated into obese and non-obese groups and then further by gender. From there, they will be put through a control, continuous exercise bout, and aerobic interval bout of exercise in a randomized order over three visits. Post exercise blood pressure, as well as other non-invasive cardiac measures will be taken over a 4 hour period.
Who can participate
Age range
18 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Healthy, inactive (defined as less than 60 min of moderate to vigorous physical activity per week)
* Men (age 18-45) and non-pregnant women (age 18-55)
* Normal BMI and waist circumference (18.5- 24.5 kg/m2 and waist \<94 cm ) OR obese (BMI \> 30kg/m2 and waist \>94 cm).
* normotensive or prehypertensive blood pressure (SBP \<140 and DBP \<90) according to JNC guidelines.
Exclusion Criteria:
* Subjects over age (men \>45, women \> 55)
* Subjects who register more than 60 minutes/week of moderate-to-vigorous physical activity via accelerometer
* Subjects who classify as hypertensive (SBP \>140 or DBP \>90)
* Subjects who answer positively (i.e. yes) on The Physical Activity Readiness Questionnaire (PAR-Q).
* Subjects with known cardiovascular, pulmonary, renal, or metabolic disease, or are having symptoms of these disease will be excluded, following current American College of Sports Medicine guidelines (ACSM).
* Current smokers
* Pregnant women
* Anyone with contraindications to vigorous exercise will be excluded from the study. -Subjects on medications used for the treatment of symptomatic cardiovascular disease will be excluded.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Postexercise Blood pressure
Timeframe: Postexercise- every ten minutes for four hours post exercise session