Software Treatments for Actively Reducing Severity of Cognitive Deficits in MDD (STARS-MDD)

Inclusion Criteria: * Primary diagnosis of recurrent Major Depressive Disorder (MDD) according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) as confirmed by MINI Version 7.0.2. * Pre-Screening (Day≤-28) Remote or In-Clinic * Screening/Day 0 (in-clinic) including: * HAM-D-17 score * BAC Symbol Coding T-test score * On stable antidepressant medication for ≥8 weeks prior to screening/baseline, with stable dose for ≥4 weeks prior to baseline/baseline, with or without stable adjunct psychotherapy (excluding DBT or CBT) for ≥12 weeks. * Access to and self-report of ability to connect wireless devices to a functional wireless network * Ability to follow written and verbal instructions (English) as assessed by the PI and/or study coordinator * Normal color vision as tested by Ishihara Color Blindness Test * Able to comply with all testing and requirements Exclusion Criteria: * Current controlled (requiring a restricted medication) or uncontrolled, comorbid psychiatric diagnosis with significant symptoms including but not limited to post-traumatic stress disorder, psychosis, bipolar illness, pervasive developmental disorder, severe obsessive compulsive disorder, severe depressive or anxiety disorder, conduct disorder, ADHD or other symptomatic manifestations that in the opinion of the Investigator may confound study data/assessments. * Initiation or completion of psychotherapy within the last 12 weeks prior to screening/baseline. The participant sh…