CompletedNot Applicable

Ultrasonographic Evaluation of Anovulatory Disorders in Lean and Overweight Women

United States59 participantsStarted 2015-08

Plain-language summary

The investigators would like to determine whether ultrasound features of the ovaries can be used to reliably diagnose different types of anovulatory disorders in women across all body types. The study will also try to establish whether ultrasound features of the ovary can reflect the degree of reproductive and metabolic problems that a woman with irregular or absent periods might be experiencing.

Who can participate

Age range

18 Years – 45 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 18-45 years * At least 2y post-menarche * BMI \>18.5kg/m2 * Good visibility of the ovaries on ultrasound Either: * Regular menstrual cycles (21-35 days); * Irregular menstrual cycles (\>35 days); or * Previous diagnosis of PCOS from a primary care provider Exclusion Criteria: * Weight \>300lbs * Currently pregnant or breast feeding * History of ovarian surgery * Use of medications or supplements known or suspected to interfere with reproductive function and/or glucose and lipid metabolism in the past 3 months * Evidence of reproductive aging as assessed by the principal criteria of STRAW+10 stages

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Follicle number per ovary

Timeframe: 1 day

Trial details

NCT IDNCT03306849

SponsorCornell University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-04

View on ClinicalTrials.gov More Menstrual Cycle Abnormal trials