CompletedPhase 3

Efficacy of Intermittent Serial Casting on Spastic Wrist Flexion Deformity

Turkey (Türkiye)34 participantsStarted 2014-11-01

Plain-language summary

Spastic wrist flexion deformity is a very common problem in children with CP. Although serial casting (SC) is one of the commonly used interventions in addition to botulinum toxin A (BoNT-A) injections and physical therapy for spastic deformities of lower extremity of children with CP, there is limited data on SC in the upper extremity. In this prospective, randomized, controlled clinical trial in order to overcome the issues with patient compliance, side effects and combined treatment options an intermittent SC model was developed. The objective of this study was to show the effects of intermittent SC when combined with occupational therapy (OT) and BoNT-A injections on spasticity, and passive range of motion (pROM) of children with CP having spastic wrist flexion deformity.

Who can participate

Age range3 Years – 18 Years

SexALL

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Inclusion Criteria: * having a diagnosis of CP according to Rosenbaum criteria, * having a unilateral spastic palmar flexion deformity of wrist joint, * having a Modified Ashworth Scale (MAS) score of 3 in the palmar flexor muscle complex, * being scheduled for BoNT-A treatment to upper extremity including palmar flexor muscle group. Exclusion Criteria: * having cognitive dysfunction, * having a history of orthopedic surgery to upper extremity, * having significant dystonia, * having infection skin breakdown, * having vascular disease, * having fracture or dislocation.

What they're measuring

Mean change from baseline Passive ROM

Timeframe: 12 weeks

Mean change from baseline MAS score

Timeframe: 12 weeks

Trial details

NCT IDNCT03306212

SponsorKocaeli University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-12-01