WithdrawnNot Applicable

Feasibility Trial in Men With Hormone Sensitive Oligometastatic Prostate Cancer

Stopped: Lack of accruals

Canada0Started 2017-09-22

Plain-language summary

Patients with hormone sensitive oligometastatic prostate cancer (≤ 5 metastatic tumours outside of regional pelvic nodes with no more than 3 in any organ system) and no previous treatment to prostate will be treated with intermittent androgen deprivation therapy +/- chemotherapy, stereotactic radiotherapy to all metastases, and either radical prostatectomy or radiotherapy.

Who can participate

Age range

18 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Able to provide informed consent. * Histologic confirmation of prostate adenocarcinoma. * Stage IV disease with ≤ 5 metastases outside of the pelvis. * ≤ 3 metastases in any one organ system. * ECOG performance 0-1. * All metastatic tumours amenable to SBRT. * Patient eligible for either RP or RT to the prostate. Exclusion Criteria: * Castration resistant prostate cancer. * Previous RP or RT to prostate. * Inability to treat all metastases with SBRT. * Prior malignancy within the past 5 years, excluding non-melanoma skin cancer, in-situ cancer, superficial bladder cancer, chronic lymphocytic leukemia or low grade lymphoma which is being observed.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Patients willing to accept their randomization

Timeframe: 2 years

Trial details

NCT IDNCT03301701

SponsorDr. Patrick Cheung

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-05-30

View on ClinicalTrials.gov More Hormone Sensitive Oligometastatic Prostate Cancer trials