CompletedNot Applicable

ICSI Versus Conventional IVF in Couples With Non-severe Male Infertility

China2,387 participantsStarted 2018-04-04

Plain-language summary

A multicenter, parallel-controlled(1:1 treatment ratio), open-label, randomized clinical trials regarding fertilization and pregnancy outcomes between ICSI and conventional IVF among couples with no-severe male-factor infertility in China.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Infertile couples scheduled for their first or second IVF/ICSI cycle. * Men with non-severe male infertility: Sperm concentration 5,000,000-15,000,000/ml or sperm with progressive motility (type A+B) 10-32%. * Women received either gonadotrophin-releasing hormone agonist protocol or gonadotrophin-releasing hormone antagonist protocol as their controlled ovarian hyperstimulation treatment. * Informed consent obtained. Exclusion Criteria: * Couple with contraindication for IVF or ICSI. * Couples receiving donor sperm or donor eggs. * Couples undergoing PGD and PGS. * Sperm concentration with progressive motility used for insemination \<100,000/ml on the day of oocyte retrieval. * Women with 0 oocytes after oocyte retrieval. * Using frozen semen. * Poor fertilization in previous cycle (≤ 25%).

What they're measuring

Ongoing pregnancy leading to live birth after the first cycle with embryo transfer

Timeframe: After 22 weeks of gestation

Trial details

NCT IDNCT03298633

SponsorJie Qiao

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-01-31

View on ClinicalTrials.gov More Male Infertility trials