CompletedNot Applicable

Peak Tidal Inspiratory Flow in Infants With Moderate to Severe Acute Viral Bronchiolitis

France50 participantsStarted 2017-11-21

Plain-language summary

This aim of this study is to measure the peak tidal inspiratory flow (PTIF), using spirometry, in young infants with moderate to severe acute viral bronchiolitis (AVB). PTIF is important to consider for the management of AVB with High Flow Nasal Cannulae (HFNC). Indeed, efficiency with HFNC is optimal provided that the settled flow is equal or higher than the patient's PTIF. However, PTIF values in infants with AVB have never been determined.

Who can participate

Age range6 Months

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Infants up to 6 months old, with AVB according to conventional clinical criteria; * Admitted to the department of Neonatal and Pediatric Intensive Care at Arnaud de Villeneuve University Hospital in Montpellier (France); * Supported with HFNC, according to the department's protocol (2 \< m-WCAS \< 5); * Not requiring immediate intubation for invasive ventilation; * Signed parental consent. Exclusion Criteria: * Infant with heart disease, cystic fibrosis or neuromuscular disorder; * Infant requiring ventilatory support with nasal continuous positive pressure (nCPAP) or with HFNC and without possibility of weaning, including for a few minutes; * Intolerance of the spirometry mask.

What they're measuring

Measurement of peak or peak inspiration flow (PTIF=peak tidal inspiratory flow)

Timeframe: 1 day but within 24 hours of patient admission

Trial details

NCT IDNCT03298217

SponsorUniversity Hospital, Montpellier

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-01-16

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