Contrast-Enhanced Subharmonic Ultrasound Imaging in Improving Characterization of Adnexal Masses in Patients Undergoing Surgery

Inclusion Criteria: * Be diagnosed with an adnexal mass * Be scheduled for surgery to remove the adnexal mass * Be clinically stable * If a female of child-bearing potential, must have a negative pregnancy test * Be conscious and able to comply with study procedures * Have read and signed the Institutional Review Board (IRB)-approved informed consent form for participating in the study Exclusion Criteria: * Females who are pregnant or nursing * Patients who have received an investigational drug in the 30 days before study drug administration, or will receive one within 72 hours (h) afterwards * Patients with known or suspected right-to-left, bi-directional, or transient right-to-left cardiac shunts * Patients with pulmonary hypertension or unstable cardiopulmonary conditions * Patients currently on chemotherapy or with other primary cancers requiring systemic or hepatic loco-regional treatment * Patients who are clinically unstable, patients who are seriously or terminally ill with a life expectancy of less than 1 month, and patients whose clinical course are unpredictable; for example: * Patients on life support or in a critical care unit * Patients with unstable occlusive disease (e.g., crescendo angina) * Patients with clinically unstable cardiac arrhythmias, such as recurrent ventricular tachycardia * Patients with uncontrolled congestive heart failure (New York Heart Association \[NYHA\] class IV) * Patients with recent cerebral hemorrhage * Patients who …