UnknownNot Applicable

Short Term Effects of Synchronized vs. Non-synchronized NIPPV in Preterm Infants.

Italy30 participantsStarted 2020-11-16

Plain-language summary

Comparing the cardio-respiratory adaptation and differences to non invasive ventilation techniques, nasal intermittent positive pressure ventilation (NIPPV) non synchronized vs synchronized (SNIPPV) in preterm newborns (gestational age at birth \< 32 weeks) at their first approach to non invasive ventilation as first intention (soon after birth) or after extubation.

Who can participate

Age range32 Weeks

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Gestational age at birth \<32 weeks * First approach to NIV ventilation (primary or after extubation) * Parent's informed consent Exclusion Criteria: * Neurological (including IVH \> 2° grade) or surgical diseases * Sepsis (clinical or laboratory confirmed) * Chromosomal or genetic abnormalities * Major malformations and congenital anomalies * Cardiac problems (including hemodynamically significant PDA) * Contraindication to NIV (i.e. nasal trauma and gastrointestinal surgery within the previous 7 days).

What they're measuring

Frequency of episodes of desaturation

Timeframe: 3 hours of NIPPV vs 3 hours SNIPPV

Trial details

NCT IDNCT03289936

SponsorUniversity of Turin, Italy

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-31

Contact for this trial

Francesco Cresi, PhD, MD

+39 11 3135781 francesco.cresi@unito.it

View on ClinicalTrials.gov More Newborn Respiratory Distress trials