Pharmacologic Treatment of Acute Episode of Schizophrenia: a Real World Study

Inclusion Criteria: * Patients meeting International Classification of Diseases (tenth version, ICD-10) criteria for schizophrenia. * acute episode; inpatients * Age from 18-65 years old (inclusion), male or female * PANSS total score at least 70 * scoring ≥ 4 on at least two of the following PANSS items: P1 (delusions), P2 (conceptual disorganisation), P3 (hallucinations), P6 (suspiciousness/persecution) ; and PANSS positive score is higher than PANSS negative score * Written informed consent Exclusion Criteria: * other serious diseases; * Pregnant or breast feeding women or planning a pregnancy * Patients in a state of drug-induced malignant syndrome or serious extrapyramidal side effect, or with a history of malignant syndrome or serious extrapyramidal side effect; * Patients who, in the opinion of the investigator, pose an imminent risk of suicide or a danger to self or others * Allergy to Aripiprazole * History of alcohol or drug abuse or dependence in the past 1-year before screening * mental retardation; bipolar disorder; major depressive disorder; * Currently using one kind of antipsychotic drug at a dose that exceeds the recommended maximum dose for two weeks, but no improvement in core symptoms; or currently using two kinds of antipsychotic drugs, at least one of which reaches or exceeds the recommended maximum dose for two weeks, but no improvement in core symptoms; or currently using three kinds of antipsychotic drugs or more; * Refractory schizophrenia patient…