RecruitingNot Applicable

Binocular Amblyopia Treatment

United States120 participantsStarted 2017-08-31

Plain-language summary

To evaluate the effectiveness of enhanced binocular amblyopia treatments in achieving a more complete and stable recovery.

Who can participate

Age range

4 Years – 10 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age 4-10 y * male and female * strabismic, anisometropic, or combined mechanism amblyopia * amblyopic eye best-corrected visual acuity 0.3-0.8 logMAR * fellow eye best-corrected visual acuity ≤0.1 logMAR * interocular visual acuity difference ≥0.3 logMAR * wearing glasses (if needed) for 8 weeks or no change visual acuity with glasses at 2 visits * 4 weeks apart. * child's ophthalmologist and family must be willing to forgo patching treatment during the 12-week study period * parent's informed consent * child must demonstrate understanding and ability to play binocular games Exclusion Criteria: * prematurity ≥8 weeks * coexisting ocular or systemic disease * developmental delay * strabismus \>5pd * any binocular amblyopia treatment in the past 3 months

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in visual acuity of the amblyopic eye

Timeframe: baseline vs 8 weeks

Trial details

NCT IDNCT03288948

SponsorRetina Foundation of the Southwest

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-31

Contact for this trial

Reed Jost, MS

2143633911 reedjost@retinafoundation.org

View on ClinicalTrials.gov More Amblyopia trials

Who can participate

Age range

4 Years – 10 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.