Cartography and Quantitative Characterization of Achilles Tendon Fibrocartilage by TE = 0ms Imagi… (NCT03287596) | Clinical Trial Compass
CompletedNot Applicable
Cartography and Quantitative Characterization of Achilles Tendon Fibrocartilage by TE = 0ms Imaging at 3T MRI
France121 participantsStarted 2018-04-07
Plain-language summary
The purpose of this study is to accurately map calcaneal fibrocartilage using TE = 0 ms imaging, and then apply measurements of our control population to SpA patients with peripheral enthesis study using the calcaneal tendon as a clinical model
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥18 years,
* Covered under social security
* Informed signed consent
Additional criteria for each group:
GROUP 1: HEALTHY VOLUNTEERS
* Absence of diagnosis of spondyloarthropathies
* No previous history of plantar support and pain, calcaneal tendinopathy, infiltration or surgery
GROUP 2: SPA + NON-SYMPTOMATICS AT THE CALCANEEN FIBROCARTILAGE LEVEL
* ASAS criteria axial or appendicular
* No previous history of plantar support and pain, infiltration or surgery
* Prescription Achile's tendon MRI with injection of contrast agent (macrocyclic gadolinium) in usual care.
GROUP 3: SPA + SYMPTOMATICS AT THE CALCANEEN FIBROCARTILAGE LEVEL
* ASAS criteria axial or appendicular
* Clinical suspicion of rheumatic enthesopathy
* Absence of a history of calcaneal infiltration or surgery
* Prescription Achile's tendon MRI with injection of contrast agent (macrocyclic gadolinium) in usual care.
GROUP 4: MECHANIC TENDINOPATHY
* Clinical diagnosis of calcaneal mechanical tendinopathy
* Absence of diagnosis of spondyloarthropathies
* No any previous history of plantar support disorder, calcaneal infiltration or surgery
* Prescription Achile's tendon MRI with injection of contrast agent (macrocyclic gadolinium) in usual care.
Exclusion Criteria:
* Age less than 18 yrs old
* Pregnant or lactating woman
* History or presence coronary pathology
* Septic arthritis
* Immunodeficiency.
* Contra-indication for MRI exam
* Legal protection
Additional criteria for GROU…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial used a special MRI technique called ZTE imaging to study the Achilles tendon — is this type of imaging available at our facility, and could it help better understand what's going on with my tendon or joint condition?
2Since this study focused on mapping Achilles tendon fibrocartilage in healthy volunteers, what does that mean for someone like me who has spondyloarthropathy or tendinopathy — could the findings from this research change how my condition is diagnosed or monitored?
3This trial is now completed and was essentially a measurement study rather than a treatment trial — are there follow-up studies building on these findings that might be more directly relevant to my care?
4Because this was a non-treatment imaging study, it doesn't test any new therapy — so what are my current standard treatment options for Achilles tendinopathy or spondyloarthropathy that I should be considering right now?
5Could the ZTE MRI technique studied in this trial give my care team more detailed information about the extent of damage to my Achilles tendon compared to what a regular MRI would show?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.