CompletedNot Applicable

Strength Training as a Supplemental Therapy of Androgen Deficiency of the Aging Male

Slovakia22 participantsStarted 2017-10-01

Plain-language summary

This study examines the effect of 12-week strength training program with and without testosterone replacement therapy (TRT) on body composition, physical function, selected biochemical markers of metabolic health, molecular parameters of training adaptation and the quality of life patients with ADAM. The investigators believe, that strength training program performed 2 times per week for 12 weeks can improve body composition (decrease fat mass and gain lean mass), muscle strength, muscle power and general quality of life in all training groups. In addition, combination TRT and strength training could help decrease fat mass, improve BMI, cardio-respiratory fitness and thus provide optimal therapy combination for hypogonadal ageing males.

Who can participate

Age range45 Years – 60 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients of secondary hypogonadism on testosterone replacement therapy, newly diagnosed patients of secondary hypogonadism. Exclusion Criteria: * Regular strength training, medical treating osteoporosis, abnormal digital rectal results, conditions which are medical contraindications (without adjusting state): diabetes mellitus, severe cardiac arrhythmia, uncontrolled hypertension, unstable angina pectoris, chronic obstructive pulmonary disease, epilepsy, unstable bone lesions with high risk of fracture, prostate cancer or abnormal serum PSA levels without adverse histological examination.

What they're measuring

Change From Baseline in Lean Mass

Timeframe: 7 days before intervention, 7 days after intervention

Trial details

NCT IDNCT03282682

SponsorComenius University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-05-30

Results submitted2020-02-23