CompletedNot Applicable

Amino Acid Digestibility of Whey and Zein Proteins

France40 participantsStarted 2017-10-01

Plain-language summary

The main goal of the study is to determine true ileal amino acid digestibility of whey protein isolate (WPI) and zein proteins in healthy subjects equipped with naso-ileal tube. The endogenous losses of proteins and amino acids will be determined by collecting digesta samples after a protein-free diet in a third group of subjects.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Normal body weight (18 \< BMI \< 30 kg.m-2) * Women or men * 18 - 65 y * Healthy * Insured under the French social security system * Signed informed consent * For women: use of birth control Exclusion Criteria: * People under trusteeship * Latex, cow milk or corn allergy A * HIV, hepatite C virus antibodies, hepatite B virus surface antigen and core antibodies positive * Pregnant women * Excessive alcohol drinking or drugs intake * Hypertension, diabetes, digestive tract, liver or renal diseases, severe heart disease * High sport practicing (\> 7h/week) * Blood donation in the 3 months prior to the study * Participation in a clinical study in the 3 months prior to the study * No signed informed consent

What they're measuring

Determination of the concentration of amino acids from dietary sources (whey or zein) in the ileal digesta collected during 9 hours after meal intake to calculate the digestibility of amino acids from whey or zein protein sources.

Timeframe: Hour 0 to 9 after intake

Trial details

NCT IDNCT03279211

SponsorInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-12-20

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