Effect of Different Instrumentation Technique on Endodontic Outcome (NCT03278054) | Clinical Trial Compass
CompletedNot Applicable
Effect of Different Instrumentation Technique on Endodontic Outcome
90 participantsStarted 2015-05-01
Plain-language summary
Aim: To evaluate and compare the outcome of primary endodontic treatment following use of different instrumentation techniques.
Materials and methods: Study subjects were recruited from the pool of patients referred for the non-surgical root canal treatment in the Department of Conservative Dentistry \& Endodontics at PGIDS, Rohtak (Haryana).
The study population comprised of patients requiring primary root canal treatment following the diagnosis of pulpal necrosis with chronic apical periodontitis in mature mandibular first and second molars.
Subjects were allocated to one of the three study groups: manual instrumentation, ProTaper instrumentation and Hybrid instrumentation.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient willing to participate in the study.
* Age greater than 18 years.
* No history of antibiotic use prior to treatment.
* Mature permanent mandibular molar having apical periodontitis requiring primary root canal treatment.
* There must be a radiographic evidence of periapical radiolucency and a diagnosis of pulpal necrosis, as confirmed by negative response to cold and electrical tests; and absence of bleeding on entering the pulp chamber.
Exclusion Criteria:
* Root canal retreatment.
* Failure to obtain authorization from patients.
* The presence of a difficult canal anatomy, internal or external resorption and immature teeth.
* Accident or complication during treatment like calcified canals, inability to achieve apical patency in any canals.
* Immuno-compromised, diabetic, pregnant and hypertensive patients.
* Periodontally compromised teeth.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Radiographic success
Timeframe: till 12 month period
2
Clinical success
Timeframe: 12 months
Trial details
NCT IDNCT03278054
SponsorPostgraduate Institute of Dental Sciences Rohtak