CompletedPhase 2

Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access

United States6 participantsStarted 2017-04-21

Plain-language summary

Hypertonic saline is used to treat elevated intracranial pressure. Intraosseous vascular access has been used to administer fluids and medications. This study combines these to administer 3% hypertonic saline via IO.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * NCCU patients in which osmotherapy with HTS is planned (standard of care * Does not already have a CVC or PICC. Exclusion Criteria: * \<18 years old * Known pregnancy * Long bone fracture in the targeted site * Proximity to prosthetic joint * Excessive tissue/absence of anatomical landmarks * History of osteopetrosis * Previous significant orthopedic procedure at site * Prosthetic limb or joint * IO catheter use in the past 48 hours of the target bone * Infection at the area of insertion * Hypersensitivity to lidocaine

What they're measuring

Number of Subjects With Tissue Damage

Timeframe: 24 hours

Trial details

NCT IDNCT03276494

SponsorOhio State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-04-21

Results submitted2019-05-10

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