Clinical Characteristics of Asthma and COPD Overlap for Patients With Asthma and COPD in Hong Kong (NCT03272932) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Clinical Characteristics of Asthma and COPD Overlap for Patients With Asthma and COPD in Hong Kong
Hong Kong1,600 participantsStarted 2017-09-15
Plain-language summary
This study is to assess the prevalence of Asthma COPD Overlap in subjects with diagnosed asthma and chronic obstructive pulmonary disease (COPD). The subsequent morbidity and mortality of subjects will be followed up for 3 years.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
Subjects must fulfil all of the following criteria:
* All patients with confirmed diagnosis of COPD (post-bronchodilator FEV1/FVC\<0.7 based on the medical records) 1 or asthma (defined as those with a consistent history and prior documented evidence of variable airflow obstruction, with evidence of an increase in FEV1 greater than 12% or 400 mL following bronchodilator or bronchial hyperresponsiveness on bronchial provocation testing, when stable) 6
* Aged \>40 years old
* Signed written informed consent to participate in the study
Exclusion Criteria:
* Patients currently with acute exacerbation of COPD by GOLD definition (any worsening of a patient's respiratory symptoms that is beyond normal day-to-day variations and requires a change in medication) 1 or acute exacerbation of asthma by GINA guideline. 6
* Patients with respiratory diseases that can show similar symptoms to chronic airway diseases such as bronchiectasis, tuberculosis (TB)-destroyed lung parenchyma, endobronchial TB, and lung cancer, or those who have history of these diseases based on physician's judgment
* Patients currently diagnosed with pneumonia and acute bronchitis
* Patients currently randomized in other clinical studies
What they're measuring
1
Percentage of prevalence of Asthma COPD overlap among the asthma and COPD subjects.