CompletedNot Applicable

Serum Progesterone on the Day of Embryo Transfer and Pregnancy Rate.

Spain1,205 participantsStarted 2017-09-08

Plain-language summary

This study aims to analyze whether serum Progsterone levels on the day of Embryo Transfer are related with Ongoing Pregnancy rate in artificial endometrial preparation cycles with intravaginal micronized progesterone.

Who can participate

Age range18 Years – 50 Years

SexFEMALE

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Inclusion criteria

✓. Age \<50 years old
✓. Hormonal Replacement therapy cycle for embryo transfer in any of the following situations:
✓. Embryos in fresh cycle with donated oocytes.
✓. Subsequent embryo transfers of vitrified embryos in cycles of donated oocytes.
✓. Frozen embryo transfers in cycles with autologous oocytes.
✓. Endometrial line: \>6.5-7mm (with trilaminar aspect) in proliferative phase, before introducing progesterone.
✓. Administration of natural micronized progesterone intravaginally (400 mg/12 hours for 5 complete days (10 dosis), before the embryo transfer and maintained until pregnancy week 12.
✓. Embryo transfer of blastocyst (day 5-6).

Exclusion criteria

✕. Uterine pathology (submucous o intramural fibroids (\>4 cm) or which deform the uterine cavity; endometrial polyps or Müllerian anomalies; or adnexal anomalies (communicating hydrosalpinx).
✕. Simultaneous participation in another clinical study.
✕. Participation in another clinical study before the inclusion in the present study, and which could affect the objectives of the present study.

What they're measuring

Concentration of serum Progesterone levels

Timeframe: The day of embryo transfer

Ongoing Pregnancies depending on Progesterone levels ranges.

Timeframe: Week 5-12 after Embryo Transfer

Trial details

NCT IDNCT03272412

SponsorInstituto Valenciano de Infertilidad, IVI VALENCIA

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-11-28

View on ClinicalTrials.gov More Ongoing Pregnancy Rate trials