ORANGE SEGMENTS: Open Versus Laparoscopic Parenchymal Preserving Postero-Superior Liver Segment Resection

Inclusion Criteria: * Patients requiring a parenchymal sparing liver resection (including wedge resections and full segmentectomies) involving one or two of segments 4a/7/8 for accepted indications . A segment 6/7 resection would also be eligible. * Able to understand the nature of the study and what will be required of them. * Men and non-pregnant, non-lactating women, aged 18 years and older. * BMI between and including 18-35 kg/m2 * Patients with ASA physical status I-II-III. Exclusion Criteria: * Inability to give (written) informed consent. * Patients requiring other liver surgery than a parenchymal sparing resection involving one or two of segments 4a, 7, 8. * Patients requiring parenchymal sparing liver resection involving segment 1. This is due to the high level of technical difficulty. * Patients with hepatic lesion(s), that are located with insufficient margin from vascular or biliary structures to be operated laparoscopically. * Patients with ASA physical status IV-V. * Repeat hepatectomy.