CompletedNot Applicable

The Basophil Activation Test as a Diagnostic Tool in Pediatric Food Allergy

France116 participantsStarted 2017-08-04

Plain-language summary

Background: The need for an oral food challenge (OFC) surrogate is growing in line with the continuous increase in the prevalence and severity of paediatric food allergy. The basophil activation test (BAT) has recently been reported as a promising tool for predicting the outcome of OFC in children. Objective: We make the hypothesis that BAT might improve the sensitivity of food allergy diagnosis and spare part of current OFC in paediatric patients attending allergy departments in Marseille APHM University hospitals. Methods: BAT will be performed in parallel with OFC in 100 paediatric patients receiving OFC during a diagnostic or follow-up procedure. Expected results: Good concordance of BAT and OFC results leading to potential OFC replacement by BAT in at least 50% of the study population

Who can participate

Age range0 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 0 - 18 years * Attending La Timone Paediatric Hospital for OFC * Social insurance * Parents and if possible child have received information and signed the consent form Exclusion Criteria: * Patients not receiving an OFC * Lack of social insurance * Inability to understand the study information * Unwilling to participate

What they're measuring

BAT positive and negative predictive values as compared with OFC

Timeframe: 2 years

Trial details

NCT IDNCT03265262

SponsorAssistance Publique Hopitaux De Marseille

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-10-04

View on ClinicalTrials.gov More FOOD ALLERGY trials