CompletedNot Applicable

Clinical Utility of Breath Tests in GI

United States1,080 participantsStarted 2011-08-31

Plain-language summary

Bloating, gas, pain and diarrhea are common complaints. Routine investigations are negative; these patients are labeled as IBS. In these patients, whether testing for carbohydrate malabsorption or small intestinal bacterial overgrowth (SIBO) is useful is unclear. Investigators aim to assess the prevalence of SIBO, fructose and lactose intolerance, the usefulness of breath tests, and predictive value of pre-test symptoms.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients over the age of 18 * Unexplained GI symptoms (gas, bloating, diarrhea, fullness, belching, and abdominal pain) * Patients who have had normal blood tests and colonoscopy, normal CT or ultrasound scan of the abdomen * Patients who have completed at least one breath test Exclusion Criteria: * Patients with previous GI surgeries (except cholecystectomy, hysterectomy, Nissen funduplication and appendectomy) * Significant comorbid medical problems (congestive heart failure, chronic renal failure, respiratory failure) * Cancer * History of recent antibiotic use (4 weeks)

What they're measuring

Small Intestinal Bacterial Overgrowth

Timeframe: 3 hour test

Positive Breath test

Timeframe: 3 hour test

Malabsorption

Timeframe: 3 hour test

Intolerance

Timeframe: 3 hour test

Normal test

Timeframe: 3 hour test

hypersensitivity

Timeframe: 3 hour test

Trial details

NCT IDNCT03261856

SponsorAugusta University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-12-31

View on ClinicalTrials.gov More Small Intestinal Bacterial Overgrowth trials