WithdrawnNot Applicable

IPV vs CPT for Airway Clearance During CF Exacerbation

Stopped: Not renewed with IRB

0Started 2018-07

Plain-language summary

Intrapulmonary Percussive Ventilation (IPV) will show greater improvements in Forced Expiatory Volume in 1 second (FEV1) shorter duration of stay, and greater time to next pulmonary exacerbation in pediatric Cystic Fibrosis patients admitted for pulmonary exacerbation. FEV1 is a measurement of obstruction in the airway which is seen to be elevated in CF patients with worsening lung disease. FEV1 is used as a primary endpoint in pulmonary trials because it is an acute indicator of worsening or improving lung function.

Who can participate

Age range5 Years – 21 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * CF patient admitted for pulmonary exacerbation Exclusion Criteria: * Patients who are not able to perform spirometry, patients with neurological impairment (Cerebral Palsy) or severe behavioral problems that precludes consistent use of IPV, patients with pneumothorax or significant hemoptysis, patients who require supplemental oxygen or ventilatory support, or patients whose parents/guardians are not willing to consent will be excluded.

What they're measuring

FEV1 change

Timeframe: duration of hospital stay (usually 10-14 days)

Trial details

NCT IDNCT03261219

SponsorUniversity of Florida

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-08-31

View on ClinicalTrials.gov More Cystic Fibrosis trials