Exercise and Nutrition to Improve Pancreatic Cancer Outcomes

Inclusion: * Individuals with suspected pancreatic or related tumor for surgical resection by pancreaticoduodenectomy, including those who've received neoadjuvant chemotherapy, are eligible provided they are approved for exercise participation by pancreatic clinic team. * Cognition and English language skills must be sufficient for completion of consent and questionnaires. * Age \>30. * Able to rise from a chair and walk household distances without assist from another person. * Willing to be randomized to one of two pre-operative home-based exercise programs, without knowing the difference between the two, and use protein supplementation if instructed. Exclusion: * Individuals are excluded if they are unsafe (according to the study team) based on current MD recommendation not to exercise, medical history, recent fracture or high-risk bone lesion, or neurologic disorder with safety concerns. * Participants cannot have an allergy to whey protein, or abnormal response to baseline physical performance tests of walking endurance and strength. * Those who currently participate in a regular and substantial (as defined by the study team) strengthening or protein supplementation program are eligible only for the 'for assessment only' observational version of the study, but will not be included in the randomized trial.