Does Inspection of Colonic Mucosa During Insertion Improve Adenoma Detection? (NCT03254030) | Clinical Trial Compass
CompletedNot Applicable
Does Inspection of Colonic Mucosa During Insertion Improve Adenoma Detection?
United Kingdom490 participantsStarted 2017-03-27
Plain-language summary
This is a prospective randomised controlled trial to assess an intervention of inspection during both phases of colonoscopic examination ( insertion and withdrawal) improve adenoma detection rate when compared to inspection only during withdrawal.
Who can participate
Age range
55 Years – 79 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Participants who are referred for a bowel scope screening procedure
Exclusion Criteria:
* Patients lacking capacity to give informed consent
* Pregnant women
* Age less than 55 years
* Uncorrectable coagulopathy
* Patients who are not fit for flexible sigmoidoscopy
* Incomplete procedure
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial tested whether inspecting the colon lining on the way in during a colonoscopy — not just on the way out — improves adenoma detection rates. Has this technique been adopted in your practice, and would it be used during my colonoscopy?
2Since this study is now completed, have the results been published, and what did they show about whether insertion-phase inspection actually found more adenomas or serrated adenomas compared to the standard approach?
3If the evidence from this trial supports inspecting during insertion, would that change how long my colonoscopy procedure takes, and is that something I should plan for?
4Given that this trial focused specifically on detecting adenomas and serrated adenomas, how does the technique studied here compare to other quality measures — like withdrawal time — that my endoscopist already uses to make sure nothing is missed?
5Would the findings from this trial be relevant to my specific situation, such as whether I'm having a screening colonoscopy versus a follow-up one after previous polyps were found?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.