CompletedNot Applicable

Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis Patients

Thailand222 participantsStarted 2017-05-01

Plain-language summary

Post extubation respiratory failure occur in 30% of extubated patients. More than 50% of them required reintubation. Noninvasive positive pressure ventilation (NIV) had been reported as an effective tool to prevent post extubation respiratory failure. Recently, high flow oxygen nasal cannula (HFNC) had been successfully used to prevent post extubation respiratory failure and prevent reintubation in comparable with NIV among post cardiothoracic surgery and high risk for reintubated patients. There was no information about HFNC versus NIV in prevention of reintubation among severe sepsis or septic shock patients.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of sepsis or septic shock according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) * Depended on mechanical ventilator for more than 48 hours * Plan for extubation due to successful weaning Exclusion Criteria: * Patient with tracheostomy * Recent upper abdominal surgery * Wound at face that prohibit face-mask application * Patient or 1st degree relative not agree to participate trial * Physician prefer either NIV or HFNC for the patient

What they're measuring

Device failure rate

Timeframe: an average of 1 year

Trial details

NCT IDNCT03246893

SponsorMahidol University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-10-31

View on ClinicalTrials.gov More Post Extubation Respiratory Failure trials